ABSTRACT
Objective:To explore the function of left atrium (LA) and left atrial appendage (LAA) in different subtypes of atrial fibrillation (AF) based on quantitative measurement using multi-slice spiral CT. Methods: Totally 71 AF patients were enrolled, including 40 with paroxysmal atrial fibrillation (PAF group) and 31 with persistent atrial fibrillation (PeAF group). The maximum volume of LAA (LAAVmax), the minimum volume of LAA (LAAVmin), the maximum volume of LA (LAVmax) and the minimum volume of LA (LAVmin) were measured using cardiac function post-processing software, and LAA ejection fraction (LAAEF), LAA ejection volume (LAAEV), LA ejection fraction (LAEF) and LA ejection volume (LAEV) were calculated. Results: LAAEF, LAEF and LAEV in PeAF group were less than those in PAF group (all P<0.01), while LAAVmax, LAAVmin, LAVmax and LAVmin in PeAF group were all larger than those in PAF group (all P<0.05). There was no significant difference of LAAEV between the 2 groups (P=0.23). LAAEF was positively correlated with LAEF in AF patients (rs=0.57, P<0.01), and negatively correlated with duration of atrial fibrillation (rs=-0.26, P=0.03). Conclusion: Multi-slice spiral CT can be used to objectively evaluate the function of LA and LAA.It has important clinical significance for understanding the functional changes of LA and LAA in different subtypes of AF.
ABSTRACT
Objective To analyze and explore the clinical efifcacy of Yixinshu capsule combined with isosorbide dinitrate tablets in the treatment of stenocardia. Method 72 patients with stenocardia in cardiovasology of Zizhong county people’s hospital of Sichuan province were randomly divided two groups,36 cases in each group. Control group was treated with isosorbide dinitrate tablets, experimental group was given both Yixinshu capsule and isosorbide dinitrate tablets. Clinical efifcacy, adverse reactions and patients’satisfaction in two groups were analyzed comparitively. Results After treatment, the total effective rate and satisfaction degree in experimental group were signiifcantly higher than control group.Incidence of adverse reactions of experimental groupwas signiifcantly lower than control group(P<0.05). Conclusion Clinical efifcacy of Yixinshu capsule combined with isosorbide dinitrate tablets in the treatment of stenocardia is signiifcantly higher than single isosorbide dinitrate tablets, with higher satisfaction degree and lower incidence of adverse reactions, which can be widely applied in clinic.